Molecular Formula | C6HCl3FNO |
Molar Mass | 228.44 |
Density | 1.640g/mLat 25°C(lit.) |
Boling Point | 238-239°C(lit.) |
Flash Point | >230°F |
pKa | -6.00±0.10(Predicted) |
Storage Condition | 0-6°C |
Refractive Index | n20/D >1.5720(lit.) |
Physical and Chemical Properties | Liquid. |
Hazard Symbols | C - Corrosive |
Risk Codes | 34 - Causes burns |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
UN IDs | UN 3265 8/PG 2 |
WGK Germany | 3 |
Hazard Note | Corrosive |
uses | intermediates of naphthyridine antimicrobial drugs. |
production method | 2, 6-dihydroxynicotinate is chlorinated with phosphorus oxychloride under the action of lithium reagent, then fluorinated and diluted with solvent, Filtration and distillation to prepare the product. |